Sağlık Bilimleri Fakültesi / Faculty of Health Sciences
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Publication Chemotherapy and radiation induced pulmonary dysfunction in hodgkin lymphoma patients(2016-12) İzmir Güner, Şebnem; Teoman Yanmaz, Mustafa; Selvi, Ahmet; Usul, ÇiğdemAlthough the deterioration in pulmonary functions is a well-known important problem due to the treatment of the Hodgkin's lymphoma patients, the immediate and long term effects of the therapy and its distinctive components were not shown clearly yet. We planned to investigate effects of multiple agent chemotherapy and/or radiotherapy to pulmonary functions immediately and thereafter and the possible effects of the managing this situation. 34 patients were included the study. The patients were evaluated for peak expiratory flow (PEF), forced expiratory volume in 1 s (FEV1), forced expiratory vital capacity (FVC), mean total lung capacity (TLC) values, FEV1/FVC ratio, diffusing capacity for carbonmonoxide (DLco), diffusing capacity for carbonmonoxide corrected for hemoglobin concentration (DLCO) before and at 1, 6 and 12 months after the initiation of the treatment. Demographic characteristics; disease stages; chemotherapy protocols; whether radiotherapy is received; if yes, the region and the dose received were recorded. The tests were finally analysed in two separated groups; group A treated with only chemotherapy and group B; treated with combination therapy, chemotherapy and radiotherapy. In group A, FVC and FEV1 is similar before and after treatment. FEV1/FVC ratio was increased (P = 0.0001) in this group despite increasing in mean TLC values (P = 0.001). No meaningful changes were observed in PEF and DLCO values in group A. In group B, FVC, FEV1 and PEF were decreased after treatment (for FVC P = 0.028, for FEV1 P = 0.04). Despite a decrease in first month of the treatment in FEV1/FVC ratio and DLco these two parameters were recovered at the end of the first year in group B patients. TLC values were increased after treatment in group B as in group A (P = 0.035). We believe that, if these patients are managed well in 1 year; necessary precautions are provided; and patients are well-informed, then there wouldn't be too much risk and mortality rate for long-term side effects of ABVD and mediastinal RT.Publication Fonksiyonel Bir Besin Olarak Turunçgiller ve Metabolik Sendrom İlişkisi(2017) Cin, Pelin; Gezer, Ceren; 264857; 227943Temel besleyici özelliklerinin yanında vücutta gösterdiği bir veya birden fazla yararlı hedef fonksiyon ile hastalık riskini azaltıp iyi hal ve sağlığı geliştirici etki gösterebilen, günlük beslenme planı içerisinde yer alıp tüketilebilen; hap, kapsül veya farklı şekillerde bir besin desteği olmayan besinlere fonksiyonel besinler adı verilmektedir. Fonksiyonel bir besin olarak turunçgiller, bileşiminde bulunan askorbik asit, folik asit, lif, pektin, potasyum, magnezyum, karotenoidler ve flavonoidler ile olumlu sağlık etkileri gösterebilmektedir. Bu bileşenlerin miktarları turunçgil çeşidine, olgunluğuna, saklama koşullarına ve işleme yöntemlerine göre değişkenlik gösterebilmektedir. Turunçgillerin sağlık üzerine olumlu etkileriyle öne çıkan bileşenleri naringin ve hesperidin flavonoidleridir. Hipertansiyon, hiperglisemi, dislipidemi, protrombotik ve proinflamatuvar faktörler, metabolik sendrom risk faktörleri arasındadır. Turunçgil flavanoidleri hiperglisemi, hiperlipidemi, hipertansiyon, inflamasyon ve vücut ağırlığı denetimi üzerine olumlu etkiler gösterebilmektedirler. Literatürde, turunçgil flavonoid ekstraktlarının kullanıldığı hayvan araştırmaları ve turunçgil tüketiminin dislipidemik etkileriyle ilgili insan araştırmaları öne çıkmaktadır. Bu nedenle günlük beslenme planında turunçgil tüketimi ve metabolik sendromla ilgili önerilerin geliştirilebilmesi için bu konuda daha fazla epidemiyolojik ve deneysel araştırmalar gereklidir.Publication Fonksiyonel Bir Besin Olarak Turunçgiller ve Metabolik Sendrom(2017-01-18) Cin, Pelin; Gezer, Ceren; 264857; 227943Temel besleyici özelliklerinin yanında vücutta gösterdiği bir veya birden fazla yararlı hedef fonksiyon ile hastalık riskini azaltıp iyi hal ve sağlığı geliştirici etki gösterebilen, günlük beslenme planı içerisinde yer alıp tüketilebilen; hap, kapsül veya farklı şekillerde bir besin desteği olmayan besinlere fonksiyonel besinler adı verilmektedir. Fonksiyonel bir besin olarak turunçgiller, bileşiminde bulunan askorbik asit, folik asit, lif, pektin, potasyum, magnezyum, karotenoidler ve flavonoidler ile olumlu sağlık etkileri gösterebilmektedir. Bu bileşenlerin miktarları turunçgil çeşidine, olgunluğuna, saklama koşullarına ve işleme yöntemlerine göre değişkenlik gösterebilmektedir. Turunçgillerin sağlık üzerine olumlu etkileriyle öne çıkan bileşenleri naringin ve hesperidin flavonoidleridir. Hipertansiyon, hiperglisemi, dislipidemi, protrombotik ve proinflamatuvar faktörler, metabolik sendrom risk faktörleri arasındadır. Turunçgil flavanoidleri hiperglisemi, hiperlipidemi, hipertansiyon, inflamasyon ve vücut ağırlığı denetimi üzerine olumlu etkiler gösterebilmektedirler. Literatürde, turunçgil flavonoid ekstraktlarının kullanıldığı hayvan araştırmaları ve turunçgil tüketiminin dislipidemik etkileriyle ilgili insan araştırmaları öne çıkmaktadır. Bu nedenle günlük beslenme planında turunçgil tüketimi ve metabolik sendromla ilgili önerilerin geliştirilebilmesi için bu konuda daha fazla epidemiyolojik ve deneysel araştırmalar gereklidir.Publication Azaltılmış Plantar Ön-Ayak Duyusunun Taban Basıncı Üzerine Etkisinin İncelenmesi(2018) Akalan, Ekin; Sert, Rukiye; Kuchimov, Shavkat Nadir; Leblebici, Gökçe; Ertürk, Gamze; Bilgili, Fuat; ÖNERGE, KÜBRA; 283338; 176320; 229941; 268636; 237820Publication Does clinically measured ankle plantar flexor muscle strength or weakness correlate with walking performance in healthy individuals?(2018) Akalan, N.Ekin; Kuchimov, Shavkat Nadir; Temelli, Yener; Ören, Merve; Nene, Anand; APTİ, ADNANOBJECTIVE: Muscle strength is usually measured using isometric hand-held dynamometers (HHDs) in the clinic. However, during functional activities, the muscle acts more dynamically. The aim of this study was to investigate the relation between clinically measured plantar flexor (PF) muscle strength (PFMS) and laboratory measurements of peak ankle plantar flexion power generation (APFPG), peak ankle moment (PAM), peak plantar flexion velocity (PFV) and mean gait velocity in healthy participants. METHODS: The maximum PFMS on non-dominant sides in 18 able-bodied persons 23.88 (SD 3.55 years) was measured before (Pre-S) and after a stretching (Post-S) procedure (135 sec. x 13 rep. with 5 sec. rest) by using a HHD. The stretching procedure was used to generate temporary PF muscle weakness. Gait analysis was carried out for Pre-S and Post-S conditions. Normalized (by weight and height) and non-normalized HHD scores and differences for both conditions were correlated by Pearson correlation coefficient calculations (p < 0.05). RESULTS: Reduced PFMS (%23, p < 0.001) in Post-S, according to the HHD scores, has only a weak correlation with APFPG (r > 0.3, p < 0.5). Gait velocity was found to be strongly correlated with APFPG only in the Post-S condition (r = 0.68, p < 0.002). HHD scores and PAM were moderately correlated with the non-normalized Post-S condition (r = 0.44, p = 0.70) and strongly correlated with the non-normalized Pre-S condition (r = 0.62, p < 0.01). DISCUSSION: HHD scores of plantar flexor muscles give very limited information about the PF performance during walking in healthy individuals. Simple normalization did not improve the relations. Clinically measured isometric muscle strength and muscle weakness have only moderate strengths for establishing a treatment protocol and for predicting performance during walking in neurologically intact individuals.Publication Osteopathic manipulative treatment improves function and relieves pain in knee osteoarthritis: A single-blind, randomized-controlled trial(Bayçınar Medical Publ-Bayçınar Tıbbı Yayıncılık, Örnek Mh Dr Suphi Ezgi Sk Saray Apt No 11 D 6, Ataşehir, İstanbul 34704, Turkey, 2018) Murat, Sadiye; Yumaşakhuylu, Yasemin; İçağasıoğlu, Afitap; ALTINBİLEK, TURGAY; 182368; 269544Objectives: In this study, we aimed to compare the efficacy of osteopathic manipulative treatment (OMT) to exercise treatment in the knee osteoarthritis (OA). Patients and methods: A total of 100 patients (9 males, 76 females; mean age 54.8 +/- 8.5 years; range, 40 to 70 years) with Stage II-III bilateral knee OA enrolled to the study and randomized into two groups between January 2015 and June 2015. Group 1 performed exercise and received OMT and Group 2 performed exercise alone. We assessed the clinical parameters with Western Ontario MacMaster Questionnaire (WOMAC) pain score, WOMAC joint stiffness score, WOMAC physical function score, Visual Analog Scale (VAS) and 50-m walking time. All patients were assessed at the beginning of the study, just after the treatment, and four weeks after the treatment. Results: There was no significant difference between groups in terms of physical examination and clinical assessment parameters before treatment. Functional improvement (p<0.05) and pain relief (p<0.05) were significantly higher in the exercise + OMT group. Conclusion: Based on our study results, OMT is a particular treatment used by osteopathic physicians to complement conventional treatment of OA of the knee. In addition to the conservative treatment, OMT can be used.Publication Hemiplejik Tip Serebral Palsili ÇocuklardaTek Ayak Üzerinde Durma Süresi İle KMFDÖ Skoru ve Stance Faz Stabilitesi Arasındaki İlişki(2018) Ertürk, Gamze; Skalan, Ekin; Evrendirek, Halenur; Karaca, Gülşah; Bilgili, Fuat; 268636; 176320; 268497; 268498; 237820Amaç: Hemiplejik-tip serebral palsili (HSP) çocukların basma fazındaki stabilite problemleri ve kaba motor gelişimindeki anormallikler çeşitli yürüyüş patolojilerine neden olmaktadır. Kaba Motor Fonksiyon Değerlendirme Ölçeği (KMFDÖ) SP'li çocuklarda fonksiyon değerlendirmesi için en sık kullanılan yöntemdir \ Yürüme stabilitesinin objektif değerlendirilmesi için pedobarografi ve 3 boyutlu yürüme analizi gibi yüksek maliyetli ve klinikte geniş alan gerektiren donanımlara ihtiyaç duyulmaktadır. Bu tür yöntemlerin uygulanması çok uzun zaman almakta, klinisyen için yorucu olmakta ve tecrübe gerektirmektedir. Tek Ayak Üzerinde Durma Testi (TADT) ise klinikte sıklıkla kullanılan, pratik ve kolay uygulanabilen ayrıca SP'li çocuklarda geçerliliği kanıtlanmış bir testtir 2. Literatürde TADT'nin KMFDÖ ve basma fazının stabilitesi arasındaki ilişkiyi değerlendiren bir çalışma yoktur. Yöntem: İstanbul Üniversitesi Çapa Tıp Fakültesi Yürüme Analizi Laboratuvarında halen takip altında olan, 7- 15 yaş arasında, Kaba Motor Fonksiyon Sınıflama Sistemine göre I ve II. seviyede, cerrahi geçmişi olmayan, 6 ay içinde Botulinium Toxin-A enjeksiyonu yapılmamış ve tek ayak üzerinde 30 saniye duramayan 18 HSP'li çocuk (yaş: 11.0812.84 yıl) çalışmaya dahil edildi. Her katılımcı TADT, KMFDÖ D / E bölümleri ile değerlendirildi ve pedobarografik ölçümleri kaydedildi. TADT sırasında katılımcılardan karşıya bakmaları ve testlenmeyen ekstremiteyi fleksiyona getirmeleri istendi (Figür 1). Test iki bacak için de 3 kere tekrarlandı ve en iyi skorlar alındı. KMFDÖ'nün D ve E bölümlerinin her bir maddesi en fazla 3 deneme yapılmasına izin verilerek değerlendirildi. En başarılı deneme 0-3 puan (0- başlatamaz, 3-tamamlar) arasında puanlandı. Pedobarografik ölçümler sırasında katılımcılar 90 BPM kadansta yürütüldü ve tepe plantar kuvvetler; T l: erken basma fazının tepe kuvveti, T2: geç basma fazının tepe kuvveti, T2-T1: tek destek fazı ( basma fazının stabilite parametresi3) olarak tanımlandı. Karşılaştırmalarda Mann Whitney - U testi, korelasyonlarda Spearman's korelasyon testi kullanıldı. Korelasyon kuvvetini belirlemek için Cohen korelasyon sınıflaması kullanıldı. Bulgular: TADT ve basma fazının stabilitesi (T2-T1) hemiplejik tarafta etkilenmemiş tarafa göre azaldı (p<0.001) (Grafik 1). Hemiplejik tarafta TADT ile basma fazı stabilitesi (T2-T1) arasında yüksek korelasyon bulundu (p=0.02, r= 0.52). Ayrıca TADT ve KMFDÖ-D arasında orta şiddetli korelasyon (p=0.05, r= 0.44); TADT ve KMFDÖ-E arasında çok yüksek korelasyon (pcO.OOl, r=0.86) bulundu. Çıkarımlar: Klinik olarak ölçülen TADT, HSP'li çocuklar için KMFDÖ D-E bölümleri ve basma fazı stabilitesi hakkında oldukça değerli bilgiler verebilir. Tek ayak üzerinde durma süresinin ölçülmesi, yürümenin basma fazı stabilitesinin anlaşılabilmesi için bilgisayarlı yürüyüş analizi, pedobarografi veya KMFDÖ 'den daha kolay ve hızlı bir yöntemdir.Publication Femoral Anteversiyon Artışı ve PesPlanovalgusu Olan Çocuklarda Tabanlığın Yürüme Kinematiğine Etkisi(2018) Evrendirek, Halenur; Akalan, Ekin; Sert, Rukiye; Kuchimov, Shavkat Nadir; Karaca, Gülşah; Ertürk, Gamze; Bilgili, Fuat; 268497; 176320; 268498; 268636; 237820Publication A novel dorsal trimline approach for passive-dynamic ankle-foot orthoses(Assoc Mechanical Engineers Technicians Slovenia, Po Box 197-Iv, Ljubljana 61001, Slovenia, 2018) Sürmen, Hasan Kemal; Fetvacı, Mahmut Cüneyt; Arslan, Yunus Ziya; AKALAN, NAZİF EKİN; 123435; 176320; 19199; 110120An ankle-foot orthosis (AFO) is an externally applied assistive device that encompasses the lower leg, ankle, and foot of the human body. In the current one-piece passive-dynamic AFO design, the trimming process is performed from lateral and medial parts of the ankle to ensure desired rotational displacement (hereafter referred to as Design I). In most cases, stress concentrations occurring over the trimmed regions during walking can cause permanent damage to the AFO. In this study, to reduce the stress concentration and ensure a homogeneous stress distribution, a new trimming approach is presented, in which the trim zones were transferred from lateral and medial to dorsal (hereafter referred to as Design II). Finite element analyses of the Designs I and II models were carried out. Displacement and von Mises stress values for both models under the same loading and boundary conditions were obtained. Maximum displacement values were 8.51 mm and 9.05 mm for Design I and Design II, respectively. Maximum stress values were 15.19 MPa and 6.70 MPa for Design I and Design II, respectively. For the similar range of motion of ankle joint, the novel design produced less stress and more homogeneous stress distribution than the currently used design, thus indicating that Design II would be more resistant to plastic deformation than Design I.Publication High hydrostatic pressure induced changes on palm stearin emulsions(Elsevier Sci Ltd, The Boulevard, Langford Lane, Kidlington, Oxford Ox5 1Gb, Oxon, England, 2018-07) Özel, Barış; Yücel, Umut; Öztop, Mecit Halil; SEVDİN, SEZEN; 163554; 202979Emulsions are thermodynamically unstable systems formed through blending of two immiscible fluids. Recent studies have shown that High Hydrostatic Pressure (HHP) can initiate or accelerate lipid crystallization in emulsions. In this study, the effect of HHP on lipid crystallization was examined. Emulsion samples were prepared with palm stearin (PS) as the oil phase and sodium caseinate (SC) as the emulsifier and they were pressurized at 100 and 500 MPa at 10, 20 and 40 degrees C for 15 min. In order to determine the crystal structure of the emulsions, differential scanning calorimeter (DSC) was used and the change in the crystal morphology during 28 day-storage at 4 degrees C was observed. Nuclear Magnetic Resonance Relaxometry (NMR) experiments were also conducted and transverse relaxation time (T-2) and self-diffusion coefficient (SDC) values showed a trend to follow polymorphic changes of lipid crystals. Results showed that pressure and storage time both had significant effects (p < 0.05) on the crystal structures of emulsions. (C) 2017 Elsevier Ltd. All rights reserved.Publication Determination of Biomechanical İnfluences of İncreased Femoral Anteversion (twisted leg) on Running for Developing İndividua(2018-08) APTİ, ADNAN; ARAT, REFİK; 259584Publication Raman and IR Spectroscopy Comlemented by Multivariate Alaysis as a Prospective tool to Investigate Biologically Relevant Materials(2018-08) ILDIZ, GÜLCE ÖĞRÜÇ; 107326This talk will illustrate the use of Raman and infrared (IR) spectroscopies, complemented by other techniques (in particular chemometrics, but also thermodynamics methods. X-ray analysis and quantum chemical calculations) to address different problems related with biologically relevant materials. First, a methodology based on IR spectroscopy and principal component analysis (PCA) will be introduced for the analysis of blood plasma samples, in order to identify spectral changes correlated with biomarkers of schizophrenia and bipolarity. Then. Raman spectroscopy, complemented by several chemometrics approaches (e.g., PCA. cluster analysis) will be shown to be a powerful, practical and elegant tool to investigate composition (in particular the lipid/protcin ratio contents) of soybean strains. Specifically, the lipid/protcin ratio contents of salt-tolerant soybean mutants will be compared with those of control groups, and the changes induced by the mutations evaluated. Finally, results of a multidisciplinary investigation on the structural, spectroscopic, photochemical and thermal properties of a series of hydantoins will be presented. Hydantoins are a family of molecules that derive from imadazolidine and that are used commonly as pharmaceuticals (as anticonvulsive. anti-inflammatory, antiepileptic and anticanccr drugs, among other uses). The study addresses the properties of the isolated molecules of the investigated compounds and also those of their neat condensed phases, with emphasis to polymorphism.Publication The relationship between orthorexia nervosa and body composition in female students of the nutrition and dietetics department(Springer International Publishing, 2018-08-29) Agopyan, Ani; Kenger, Emre Batuhan; Ülker, Mutlu Tuçe; Uzsoy, Mustafa Ataberk; Küçük Yetkin, Meral; KERMEN, SEDA; 58275; 258944; 268496; 202390This study was carried out to determine the relationship between orthorexia nervosa (ON) and eating disorder and body composition, class level, and place of residence in university students from the Department of Nutrition and Dietetics. The participants (n = 136; 20.9 ± 2.0 years) were all female students, whose scores on the Orthorexia Nervosa Questionnaire (ORTO-11) and the Eating Attitudes Test (EAT-40) indicated a prevalence of ON and eating disorder. Assessment of body composition indices (Tanita bioelectrical impedance; SC-330) of the participants showed there to be no significant difference in the EAT-40 and ORTO-11 scores in terms of body composition, class level, and place of residence. A large majority of the participants (70.6%) had high ORTO-11 scores, and a significant negative correlation (p < 0.05) was identified between the EAT-40 and ORTO-11 scores. Final results from analysis of the data showed that although abnormal orthorexic tendencies were common among the students from the Department of Nutrition and Dietetics, they were nonetheless able to maintain body composition within normal values.Publication Does One Leg Standing Duration Have Relation With GMFM Scores and Stability in Stance Phase for Hemiplegic Children ?(2018-09) N. Ekin Akalan; Halenur, Evrendilek; Karaca, Gülşah; Bilgili, Fuat; Ertürk, Gamze; 268636; 176320; 268497; 268498; 237820This paper reports the results of a study to validate a measure of gross motor function in detecting change in the motor function of disabled children. Physiotherapists used this instrument to assess 111 patients with cerebral palsy, 25 with head injury and 34 non-disabled preschool children on two occasions, the second after an interval of four to six months. Parents and therapists independently rated the children's function within two weeks of each assessment, and a sample of paired assessments was videotaped for 'blind' evaluation by therapists. Correlations between scores for change on this measure and the judgments of change by parents, therapists and 'blind' evaluators supported the hypothesis that the instrument would be responsive to both negative and positive changes.Publication Distinguishing the Influences of Increased Femoral Anteversion From Hypermobility During Walking For Neurologically Intact Individuals(2018-09) Akalan, Ekin; Karaca, Gülşah; Kuchimov, Shavkat Nadir; Bilgili, Fuat; Temelli, Yener; Leblebici, Gökçe; Ertürk, Gamze; Evrendirek, Halenur; ÖNERGE, KÜBRA; APTİ, ADNAN; 176320; 268498; 259584; 237820; 190878; 229941; 283338; 268636; 268497Increased femoral anteversion (IFA) is a transverse plane problem that may lead to alterations on lower body kinematics during walking (1,2). IFA and hypermobility syndrome are commonly seen together in healthy individuals (3). Therefore, describing the pure effects of IFA related gait parameters is very difficult for children with hypermobility and IFA together.Publication The Effects of the Intoeing Gait Pattern onPlantar Pressure Behavior and Foot Postur(2018-09) Akalan, Ekin; Sert, Rukiye; Kuchimov, Shurubu; Bilgili, Fuat; APTİ, ADNAN; 176320; 259584; 237820Publication Sağlıklı Çocuklarda Femoral Anteversiyon Artışının Hipermobilite Sendromundan Bağımsız Olarak Yürüme Parametrelerine Etkileri(2018-09) Karaca, Gülşah; 268498Introduction Increased femoral anteversion (İFA) is a transverse plane problem that may lead to alterations on lower body kinematics during walking (1,2). IFA and hypermobility syndrome are commonly seen together in healthy individuals (3). Therefore, describing the pure effects of IFA related gait parameters is very difficult for children with hypermobility and IFA together. Methods Sixty-seven participants were divided into four groups; 1)Twenty-eight hypo-mobile IFA children (Thoracantheric-Promience-Test(TPAT):45±4.2°) whose Beighton-score were <4 (IFA<4) (Age: 10.3±3.7y.o,Beighton:2.6±1.1), 2) Twenty-eight hyper-mobile IFA children (TPAT:45.5±6.5°) with Beighton Score >6 (IFA>6) (Age:7.7±3.7y.o, Beighton:7.8±0.9), 3)Seven hypo-mobile TDC (Hip-internal-rotation:<50°, TPAT: 19.1 ±8.3°) with Beighton-score <4 (N<4)(Age:12.1±1.4y.o, Beighton: 1.1 ±1.6) and 4)Five hyper-mobile TDC (TPAT:28.0±5.0°) with Beighton-score >6 (N>6) (Age:9.0±1.2y.o, Beighton:6.8±0.8), The pelvic, hip, knee and ankle kinematics and temoporal-spatial parameters were analyzed by 3D Motion Analysis in self-selected speed with Davis protocol (4). All participants with IFA had hip-internal-rotation:>65°, and external hip rotation angle >20°. Mann Whitney U and paired t test were used for comparison (p<0.05). The same parameters in which significantly changed between IFA<4 and N<4 and comparison of IFA<6 and N>6 were considered as pure IFA related gait parameters. Results Pure IFA affects were found as increasing peak dorsiflexion angle in swing, hip internal rotation in stance and peak pelvic external rotation and pelvic rotation range (Table 1). The hyper mobility related gait parameters were increased knee flexion at initial contact and peak knee extension, decreased peak and mean hip rotation and time of toe-off in stance. Discussion This study, the first in the literature, distinguished the IFA related gait parameters from hyper-mobility affects. Whether the hyper-mobility involves the IFA or not, IFA augments hip internal rotation, pelvic external rotation and increase the peak dorsiflexion in swing. Even though velocities are similar in all groups, IFA also may cause to set earlier toe-off time. In TDCs, only temporal-spatial parameters were found as changed, which may due to limited participation in TDC groups. Hypermobility may be a compensatory factor that decreases the enhanced hip internal rotation during walking for neurologically intact children with increased femoral anteversion.Publication "How Does Hypermobility Affect Lower Extremity Function for Children with Increased Femoral Anteversion? Describing Effects ofReduced Forefoot Sensation on Foot Pressure Distribution: Plot Study(2018-09) Leblebici, Gökçe; Akalan, Ekin; Kuchimov, Shavkat Nadir; Kurt, Rengin Aslıhan; ÖNERGE, KÜBRA; APTİ, ADNAN; 283338; 229941; 259584; 272694; 283338Increased femoral anteversion (IFA) and joint hypermobility are commonly seen together in pediatric clinics. Femoral anteversion and joint hypermobility may contribute falling and fatigue in activities, as well as causing abnormal gait patterns.Publication O 043 – Mechanics of spastic semitendinosus altered by intermuscular interactions elevate its contribution to pathological resistance against knee extension during gait(2018-09) Kaya, C.S.; Bilgili, Fuat; Temelli, Yener; Ateş, Filiz; Yücesoy, Can A.; AKALAN, NAZİF EKİNPublication The Infulence on Hypermobility on Children with Increased Femoral Anteversion: Static and Dynamic Foot Pressure Behavior(2018-09) Akalan, Ekin; Kurt, Rengin Aslıhan; Sert, Rukiye; Leblebici, Gökçe; Kuchimov, Shavkat Nadir; Bilgili, Fuat; Temelli, Yener; Miller, Freeman; ÖNERGE, KÜBRA; APTİ, ADNAN; 176320; 259584; 283338; 229941; 237820; 190878Increased femoral anteversion (IFA) is the forwardly rotated femoral head relative to transcondilar axis of the knee(1). IFA and hypermobility syndrome are seen together in pediatric clinic(2). For IFA children, effects of hypermobility on plantar pressure behavior during walking are absent in the literature.