Sağlık Bilimleri Fakültesi / Faculty of Health Sciences
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Browsing Sağlık Bilimleri Fakültesi / Faculty of Health Sciences by Type "Article Early Access"
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Publication Anxiolytic-Like Effects of Extremely Low Frequency Electric Field in Stressed Rats: Involvement of 5-HT2C Receptors(Taylor & Francis Ltd., 2022) Kantar, Deniz; Acun, Alev Duygu; AFŞAR, EBRU; Yargıçoğlu, PirayeBackground Possible modulatory effects of noninvasive brain stimulation have gained interest recently. In our study, the effect of low frequency electric fields (LF-EF) on stress-induced electrophysiological, behavioral changes and the possible involvement of serotonergic 5-HT2C receptors were investigated. Materials and methods A total of eight groups including the control groups were formed by applying LF-EF with or without a 5-HT2C receptor agonist to naive or acute stress exposed rats to demonstrate the effects of LF-EF. LF-EF administration at 10 kV/m was started 30 min before acute stress application and lasted for 1 h in total. Anxiety levels and social interaction were evaluated using the elevated plus maze test and social interaction test, respectively. Auditory evoked potentials (AEP) were recorded by using ascending loudness paradigms. Loudness dependence AEP (LDAEP) was calculated by using amplitude values to analyze serotonergic transmission. Serotonin and glucocorticoid levels were measured in the frontal cortex and hippocampus. Results It was observed that the applied LF-EF reduced the anxiety behavior, and attenuated the LDAEP responses in stress and/or 5-HT2C receptor agonist applied groups. In parallel, an increase in serotonin levels and a decrease in glucocorticoid levels were observed. However, LF-EF exposure was ineffective in impaired social interaction. Conclusions Our findings show that 10 kV/m LF-EF administration may modulate the neural network and physiological responses associated with mild acute stress. 5-HT2C receptor dependent functions are thought to play a role in the anxiolytic effect of LF-EF.Publication Arteriovenous Fistula Self-Care Behaviors in Patients Receiving Hemodialysis Treatment: Association With Health Literacy and Self-Care Agency(Sage Publications Ltd., 2022) Bülbül, Elif; Ayvaz, Meryem Yıldız; Yeni, Tuğba; TÜREN, SEVDA; Efil, SevdaBackground: Arteriovenous fistula-related self-care behaviors, self-care agency and health literacy are important for vascular access patency, which is vital in the continuation of hemodialysis treatment. The purpose of this study was to determine the arteriovenous fistula-related self-care behaviors of patients receiving chronic hemodialysis treatment and the relationship between these behaviors and their health literacy and self-care agency levels. Methods: In this descriptive correlational study, the data were collected from 216 chronic hemodialysis patients. Results: The rate of the patients who had good self-care behaviors levels was 83.96%. The sociodemographic variables that were significantly related to AVF-related self-care behaviors were education, employment status and age. It was found that the patients who had had AVF for a longer time had better self-care behaviors regarding their management of symptoms and findings (p < 0.05). As the self-care agency of the patients (r = 0.612, p < 0.001) and their health literacy (r = 0.421, p < 0.001) increased, their AVF-related self-care behaviors also increased. Conclusion: Age, education status, health literacy and self-care agency were identified to affect AVF-related self-care behaviors.Publication Assessment of the Correlation Between Weight Status and the Frequency of Dietician Interviews in Sleeve Gastrectomy Patients(Springer, 2021) BATAR, NAZLI; SEVDİN, SEZEN; Güçlü, Duygu; KERMEN, SEDAPurpose The aim of this study was to evaluate the relationship between the weight status of sleeve gastrectomy patients during the first two postoperative years and the frequency of dietician interviews. Materials and Methods This was a retrospective cross-sectional study, and the subjects were patients who had surgery at a special obesity clinic, Bariatriklab, in Istanbul, Turkey, between February 01, 2014, and February 01, 2018.The mean age +/- standard deviation of the participants was 38.8 +/- 11.9 years. The mean body mass index (BMI) +/- standard deviation was 44.2 +/- 6.1 kg/m(2)preoperatively. The preoperative (pre-op) and 12-, 18-, and 24-month postoperative (post-op) weights and the frequency of interviews with dieticians for 2 years after the operation were collected, and statistical analysis was performed using SPSS ver. 23.0. Results A total of 247 laparoscopic sleeve gastrectomy (LSG) patients, 161 women (65.2%) and 86 men (34.8%), were evaluated in this study. As the frequency of dietician interviews increased in the first year, the amount of excess weight loss (EWL) increased in the second year (p < 0.01). In addition, as the frequency of dietician interviews increased in the second year, the amount of EWL in the second year decreased (p < 0.01). The frequency of dietician counseling among participants who did not experience weight loss between 12 and 24 months was significantly higher than that among those who experienced weight loss (p < 0.05). Conclusion It should not be forgotten that bariatric surgery requires teamwork, and patients should be cared for with an interdisciplinary approach. Dieticians play an important role in changing nutritional habits and making them sustainable.Publication Cross-Cultural Adaptation, Reliability, and Validity of a Turkish Version of the Work Rehabilitation Questionnaire (WORQ-Turkish)(Springer Plenum, 2021) Aran, Orkun Tahir; Abaoğlu, Hatice; Çağlar, Gamze Ekici; AKEL, BURCU SEMİN; Aki, Esra; Karahan, Sevilay; Kayıhan, HülyaPurposeThe Work Rehabilitation Questionnaire (WORQ) is an instrument based on the International Classification of Functioning Vocational rehabilitation core set. The aim of this study was to analyze the validity, reliability and cross-cultural adaptation of the WORQ to Turkish and evaluate its psychometric properties.MethodsThe cross-cultural adaptation and translation procedures were conducted following Beaton's guidelines. The test-re-test reliability was examined by Spearman Brown Coefficient (split half analysis), internal consistency was examined by Cronbach's alpha. Criterion related validity of the WORQ was determined by Beck Depression Inventory using Pearson correlation coefficient and known group differences regarding age, gender, work and educational levels using one-way ANOVA and t test. Construct validity was examined by confirmatory factor analysis using AMOS.ResultsTwo hundred and fifty-seven participants with disabilities were included to the study from seven different provinces of Turkey. The WORQ-Turkish showed excellent internal consistency (0.906), good test-retest reliability (0.811), and good construct validity (good model fit indices). Criterion related validity analysis showed medium correlations between WORQ and Beck Depression Inventory (p < 0.001), however there were no statistical significant differences regarding known group parameters (p > 0.05).ConclusionsIn this study, the cross-cultural adaptation, and validity and reliability of WORQ-Turkish self-reported version were examined and the results indicated that WORQ-Turkish was a valid and reliable scale for analyzing vocational rehabilitation process of people with disabilities.Publication Cultural Beliefs of Turkish Women for Breast Cancer and Screening(SAGE Publications Inc., 2021) Tosun, Hale; Andsoy, Işıl Işık; GÜL, ASİYEIntroduction: Breast cancer is an important health problem and early diagnosis is important in its treatment. Women's approach and cultural beliefs are effective in ensuring early diagnosis. This study examined psychometric properties of the Ferrans Cultural Beliefs Scale and assessed cultural beliefs on breast cancer and screening programs among Turkish women. Method: The study was performed in a descriptive and cross-sectional design with 420 women using the Ferrans Cultural Beliefs Scale that is considered reliable and valid in Turkey. Results: The mean total score of the Ferrans Cultural Beliefs Scale was 3.24 +/- 3.16. The highest "yes" responses were for the statement "If breast cancer is treated correctly, it can be cured" (n = 387, 92.1%). Discussion: This study, which is the first in Turkey, highlights the importance of measuring the effects of Turkish healthy women's cultural beliefs in breast cancer and screening for early diagnosis. Determining women's cultural beliefs will make known the attitudes and behaviors toward breast cancer, so that the nurse will provide sensitive and effective nursing care, develop nursing knowledge, and integrate this knowledge with clinical practice.Publication Determination of Factors Affecting Time in Therapeutic Range in Patients on Warfarin Therapy(Sage Publications Inc., 2023) TÜREN, SEVDA; Türen, SelahattinBackground The effectiveness and safety of warfarin depend on maintaining an international normalized ratio (INR) within the therapeutic range. Time in Therapeutic Range (TTR) is defined as the percentage of time a patient's INR is within the therapeutic range. Objective We sought to determine the factors affecting good TTR in patients on warfarin therapy. Methods This was a descriptive cross-sectional study conducted in a single tertiary care center. Good anticoagulation control was defined as TTR >= 65%. Results The study population consisted of 518 patients. The mean age was 57.6 +/- 12.3 (19-87) and 54.4% of the patients were female. 47.5% patients achieved good anticoagulation control (TTR >= 65%). The mean Medication Adherence Report Scale (MARS) score was significantly higher in patients with good TTR (23.5 +/- 1.9 vs. 22.8 +/- 2.1, p = .002). Only 40.2% of the patients received education on warfarin. In multivariable analyses, the duration of warfarin therapy >10 years (OR: 2.27, 95% CI: 1.34-3.84, p = .002) and MARS score (OR: 1.22, 95% CI: 1.09-1.35, p < .001) were found to be the independent predictors of the good anticoagulation control. Conclusion Duration of warfarin therapy >10 years and MARS score were the independent predictors of good anticoagulation control.Publication The Effect of Kinesiophobia on Physical Activity, Balance, and Fear of Falling in Patients with Parkinson's Disease(Taylor & Francis Inc., 2022) Oğuz, Semra; UZUNOĞLU, GAMZE ERTÜRK; Polat, Mine Gülden; Apaydın, HülyaPurpose Kinesiophobia is defined as the fear of movement and activity resulting from a feeling of vulnerability to painful injury or re-injury. This study aimed to determine the effect of kinesiophobia on physical activity, balance, and fear of falling in patients with Parkinson's disease. Methods The study, which was designed as a cross-sectional type, was conducted with 86 patients with Parkinson's disease (age 61.25 SD [9.72] years old) by face-to-face interviews with the patients. The Tampa Scale of Kinesiophobia, International Physical Activity Questionnaire-Short Form, Berg Balance Scale, Falls Efficacy Scale, Visual Analog Scale - Fear of Falling, Unified Parkinson's Disease Rating Scale - motor score, and the Hoehn and Yahr scale were used to evaluate the patients. Results Patients with Parkinson's disease who had high levels of kinesiophobia had lower levels of physical activity, worse balance, and higher disease severity and fear of falling. A correlation was found between the Tampa Scale score and physical activity, balance, fear of falling, falls efficacy, and disease motor score (p r = -0.38, -0.54, 0.67, 0.57, and 0.37, respectively). According to multiple linear regression analysis, kinesiophobia explained the dependent variables to varying degrees ranging from 13% to 44% (p < .001). Conclusions Patients with Parkinson's disease may have kinesiophobia. Rehabilitation programs to support functional capacity for these patients should be developed considering the presence of kinesiophobia.Publication Relationship Between Weight Loss and Dietary Inflammatory Index and Serum C-Reactive Protein Level Before and After Bariatric Surgery(Mary Ann Liebert, Inc., 2022) BATAR, NAZLI; ÖZTÜRK, ELİF SILA; Yıldız, Nida; SEVDİN, SEZENBackground: This study aims to evaluate the relationship between weight loss, dietary inflammatory index (DII), and serum C-reactive protein (CRP) levels in patients who underwent sleeve gastrectomy (SG).Materials and Methods: This research is a retrospective cross-sectional study. We enrolled patients who had obesity surgery in a private clinic in Istanbul, Turkey, between February 1, 2014, and February 1, 2018. Pre-operative (pre-op) and 12th, 18th, and 24th month post-operative (post-op) weight, nutritional consumption, and CRP levels of the participants were evaluated. The DII scores of the individuals were calculated from the obtained dietary data.Results: In this study, a total of 140 SG patients, 100 women and 40 men, were evaluated. It was found that there was a positive and significant correlation between the decreasing body mass index (BMI) value and CRP value of the individuals. It was concluded that for all measurements of BMI, excessive weight loss, DII, and CRP, at least one measurement significantly differentiated from the other measurements. Post-op 18th month DII was significantly higher than the post-op 24th month DII value.Conclusions: Long-term follow-up of patients by a multidisciplinary team in the pre-op and post-op periods is required to ensure success in bariatric surgery results. Dieticians play an important role in changing and sustaining eating habits.Publication "Sleep Quality and Depression Level in Nurses in COVID-19 Pandemic"(Sage Publications Inc., 2022) Tosun, Ayşe; Tosun, Hale; Özkaya, Birgül Ödül; Erdoğan, Zeynep; GÜL, ASİYEThe COVID-19 spread rapidly all over the world and pandemic process has negatively affected nurses. Sleep disorders and depression are among these negative effects. Managers' awareness of problems experienced by nurses and taking precautions will increase employee and patient satisfaction and provide quality patient care. The study was conducted in descriptive, cross-sectional and correlational design to explain nurses' sleep quality and depression levels and relationship between them during the COVID-19 pandemic with 142 nurses who completed Personel Information Form, Pittsburgh Sleep Quality Index (PSQI) and Beck Depression Index (BDI). Sleep quality of nurses (64.8%) was poor, 33.1% had depression, and high school education, having a chronic illness and PSQI score increased the risk of depression level of nurses. Results highlight COVID-19 pandemic affected nurses' sleep quality and depression levels. All managers should be pioneers in providing psychological support to nurses and preparing and implementing a program for prevention of insomnia and depression.