Publication:
A Molecular Mechanics Conformational Study of Peptide T

Placeholder

Organizational Units

Program

Authors

Godjayev, Niftali M.
Akverdieva, G.

Advisor

Language

Publisher:

Journal Title

Journal ISSN

Volume Title

Abstract

Conformational behaviour of peptide T, a competitor of the human immuno-deficiency virus in the binding to human T cells, was investigated by theoretical conformational analysis. Two types of conformations are found to be the most stable: quasi cyclic conformation, which is favourable for intensive electrostatic interaction between the charged terminal groups, and spiral conformation, which provides optimal nonvalent interaction of atoms of the polypeptide skeleton. A β-turn of the polypeptide chain was revealed on the section Thr4-Tyr7.

Description

Source:

Keywords:

Citation

Endorsement

Review

Supplemented By

Referenced By

1

Views

0

Downloads