Publication: Effects of polyamines and polyamine biosynthetic inhibitors on mitotic activity of Allium cepa root tips
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Date
2008-03
Authors
Ünal, Meral
Palavan Ünsal, Narçin
Tüfekçi, M. A.
Journal Title
Journal ISSN
Volume Title
Publisher
AKADEMIAI KIADO, PRIELLE K U 19, H-1117 BUDAPEST, HUNGARY
Abstract
The genotoxic and cytotoxic effects of exogenous polyamines (PAs), putrescine ( Put), spermidine (Spd), spermine (Spm) and PA biosynthetic inhibitors, alpha-difluoromethylornithine ( DFMO), cyclohexilamine (CHA), methylglioxal bis-(guanylhydrazone) ( MGBG) were investigated in the root meristems of Allium cepa L. The reduction of mitotic index and the induction of chromosomal aberrations such as bridges, stickiness, c-mitotic anaphases, micronuclei, endoredupliction by PAs and PA biosynthetic inhibitors were observed and these were used as evidence of genotoxicity and cytotoxicity.
Description
Keywords
allium cepa, chromosome aberration, mitotic activity, polyamine, polyamine biosynthetic inhibitor, cell-cycle, spermidine, growth, seedlings, plants, kromozom aberasyon, mitotik aktivite, poliamin, poliamin biyosentetik inhibitörü, hücre döngüsü, büyüme, fidan, bitkiler