Pehlivanlı, Ayça C.İbrikçi, TurgayErsoy, Okan K.2020-04-072020-04-07200820054990https://hdl.handle.net/11413/6323A special consensual approach is discussed for separating a molecular group with a proven pharmacological activity from another molecular group without any activity. It is mainly a group decision to produce a consensus of multiple classification results obtained with a single classification algorithm. For this purpose, the constructed model has a preprocessing unit which consists of transformation of input patterns by random matrices and median filtering to generate independent errors for a single type of classifier and postprocessing for consensus. The neural network based consensus classifier operating with MOE descriptors was applied to a set of 641 chemical structures. The confirmed drugs were classified with an accuracy of 86.54% while nondrugs resulted in 82.67% accuracy.en-USAttribution-NonCommercial-NoDerivs 3.0 United Stateshttp://creativecommons.org/licenses/by-nc-nd/3.0/us/Consensual classification of drug and nondrug compoundsArticle