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Roscovitine treatment inhibited cell proliferation and induced apoptosis via modulating activity of Stat3 and Foxo1 under control of Akt in LNCaP prostate cancer cells 

Arısan, Elif Damla; Gümüşkaptan, Çağrı; Berrak, Özge; Obakan Yerlikaya, Pınar; Çoker Gürkan, Ajda; Ünsal, Zeynep Narçin (2015)
Cyclin dependent kinases (CDKs) are known activators of nuclear hormone receptors; such as androgen receptor (AR) via modulating several cell survival signaling routes. However, novel CDK inhibitors might also prevent cell ...
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Epibrassinolide Treatment Caused Autophagy or Apoptosis Decision in a Time-Dependent Manner through ER Stress in Colon Cancer Cells 

Obakan Yerlikaya, Pınar; Adacan, Kaan; Arısan, Elif Damla; Çoker Gürkan, Ajda; Ünsal, Zeynep Narçin (2017)
Epibrassinolide (EBR) is a natural plant polyhydroxysteroid with structural similarity to steroid hormones. Lately we showed by SILAC assay that EBR treatment induces apoptosis by significantly altering the expressions of ...
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Celastrol Modulates Lipid Synthesis via PI3K/Akt/mTOR Signaling Axis to finalize Cell Death Response in Prostate Cancer Cells 

Arısan, Elif Damla; Rencüzoğulları, Özge; Çoker Gürkan, Ajda; Obakan Yerlikaya, Pınar; Ünsal, Zeynep Narçin (2017)
FASN is key enzyme during lipid biogenesis is associated with prostate cancer. In this study, we aim to investigate the potential role of celastrol, root extracts of Tripterygium wilfordii on modulation of lipid ...
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Autocrine Growth Hormone-Triggered Curcumin Resistance Abolished by NF-κB Signaling Pathway Dependent on Inflammatory Cytokines and Active Polyamine Catabolic Machinery in MCF-7, MDA-MB-453 and MDA-MB-231 Breast Cancer Cells 

Çoker Gürkan, Ajda; Çelik, Merve; Uğur, Merve; Arısan, Elif Damla; Obakan Yerlikaya, Pınar; Ünsal, Zeynep Narçin (2017)
Autocrine Growth Hormone (GH) induces cell growth, proliferation metastasis in breast cancer. Curcumin is a promising therapeutic agent in cancer through affecting different molecular targets. Our aim was to demonstrate ...
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Prognostic value of free/total PSA ratio in prediction of bone metastases in patient with prostate cancer 

Özdemir, Semra; Tan, Yusuf Ziya; Ersay, Ahmet Reşit; Koç Öztürk, Fulya; Özdemir, Beril Su (2018-08-30)
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Endoplasmic reticulum stress is activated after epibrassinolide treatment leading autophagy in wild type and Atg5­/­ mouse embryonic fibroblasts: a survival mechanism in non­malignant cells. 

Adacan, Kaan; Obakan Yerlikaya, Pınar; Arısan, Elif Damla; Çoker Gürkan, Ajda; Ünsal, Zeynep Narçin (2017)
Autophagy is a process of cellular self­degradation during which macromolecules, damaged/aged organelles and proteins are delivered to the lysosome by engulfment within double­membrane vesicles. The accumulation of ...

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AuthorArısan, Elif Damla (5)Obakan Yerlikaya, Pınar (5)Çoker Gürkan, Ajda (5)Ünsal, Zeynep Narçin (5)Adacan, Kaan (2)Berrak, Özge (1)ERSAY, AHMET RESIT (1)Gümüşkaptan, Çağrı (1)KOÇ ÖZTÜRK, Fulya (1)Rencüzoğulları, Özge (1)... View MoreSubjectapoptosis (2)autophagy (1)breast cancer (1)celastrol (1)colon cancer (1)curcumin (1)epibrassinolide (1)FASN (1)NF-κB (1)Polyamine (1)... View MoreDate Issued2017 (4)2015 (1)2018 (1)Has File(s)
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İstanbul Kültür University

Hakkında |Politika | Kütüphane | İletişim | Send Feedback | Admin

Istanbul Kültür University, Ataköy Campus E5 Karayolu Üzeri Bakırköy 34158, İstanbul / TURKEY
Copyright © İstanbul Kültür University

Creative Commons Lisansı
IKU Institutional Repository, Creative Commons Alıntı-GayriTicari-Türetilemez 4.0 Uluslararası Lisansı ile lisanslanmıştır.

Designed by  UNIREPOS