Now showing items 21-30 of 34
Fetuin-A 742 (C/T) and 766 (C/G) polymorphic sites are associated with increased risk of myocardial infarction in older patients (40 years of age)
(Spandidos Publ Ltd, Pob 18179, Athens, 116 10, Greece, 2015-07)
Inflammation and genetics have key roles in the pathogenesis of atherosclerosis, and the etiology of myocardial infarction (MI). Recent studies have indicated that lower serum levels of fetuin-A may accelerate the vascular ...
Investigation the potential role of FoxO members in the purvalanol and roscovitine-induced autophagy in LNCaP and DU 145 prostate cancer cells
(Wiley-Blackwell, 111 River St, Hoboken 07030-5774, NJ USA, 2015-07-04)
Orlistat is a fatty acid synthase (FASN) inhibitor caused the modulation of AMPK and lipogenesis signaling axis in PC3 prostate cancer cells but not in PNT1A prostate epithelial cells
(Wiley, 111 River St, Hoboken 07030-5774, NJ USA, 2017-09)
Purvalanol induces endoplasmic reticulum stress-mediated apoptosis and autophagy in a time-dependent manner in HCT116 colon cancer cells
(Spandidos Publ Ltd, Pob 18179, Athens, 116 10, Greece, 2015-06)
Purvalanol, a novel cyclin-dependent kinase inhibitor, is referred to as a strong apoptotic inducer which causes cell cycle arrest in various cancer cells such as prostate, breast and colon cancer cell lines. Various ...
Epibrassinolide alters PI3K/MAPK signaling axis via activating Foxo3a-induced mitochondria-mediated apoptosis in colon cancer cells
(Elsevier Inc, 525 B Street, Ste 1900, San Diego, Ca 92101-4495 Usa, 2015-10-15)
Epibrassinolide (EBR), a steroid-derived plant growth regulator, has been recently suggested as an apoptotic inducer in different cancer cells. In this experimental study, we investigated the potential apoptotic effect of ...
SILAC-Based Mass Spectrometry Analysis reveals that Epibrassinolide induces apoptosis via activating Endoplasmic Reticulum stress in prostate cancer cells
(Public Library Science, 1160 Battery Street, Ste 100, San Francisco, Ca 94111 Usa, 2015-09-09)
Epibrassinolide (EBR) is a polyhydroxylated sterol derivative and biologically active compound of the brassinosteroids. In addition to well-described roles in plant growth, EBR induces apoptosis in the LNCaP prostate cancer ...
Curcumin Prevented Human Autocrine Growth Hormone (GH) Signaling Mediated NF-κB Activation and miR-183-96-182 Cluster Stimulated Epithelial Mesenchymal Transition in T47D Breast Cancer Cells
Autocrine growth hormone (GH) signaling is a promoting factor for breast cancer via triggering abnormal cell growth, proliferation, and metastasis, drug resistance. Curcumin (diferuloylmethane), a polyphenol derived from ...
Orlistat as a fatty acid synthase inhibitor blocks cell survival mechanism via activating PTEN, which controls PI3K/AKT/MAPK axis in PC3 prostate cancer cells
(Elsevier Science Bv, Po Box 211, 1000 AE Amsterdam, Netherlands, 2017-08-30)
Curcumin inhibits autocrine growth hormone-mediated invasion and metastasis by targeting NF-kappa B signaling and polyamine metabolism in breast cancer cells
Curcumin is assumed to be a plant-derived therapeutic drug that triggers apoptotic cell death in vitro and in vivo by affecting different molecular targets such as NF-kappa B. Phase I/II trial of curcumin alone or with ...
EBR induced autophagy in colon carcinoma cell lines
(Wiley-Blackwell, 111 River St, Hoboken 07030-5774, Nj Usa, 2015-07)