Now showing items 1-2 of 2
Inhibition of extracellular signal-regulated kinase potentiates the apoptotic and antimetastatic effects of cyclin-dependent kinase inhibitors on metastatic DU145 and PC3 prostate cancer cells
(Wiley Online Library, 2018-10-15)
Purvalanol and roscovitine are specific cyclin‐dependent kinase (CDK) inhibitors,which have antiproliferative and apoptotic effects on various types of cancer.Although, the apoptotic accomplishment of purvalanol and ...
Downregulation of c-Myc mediated ODC expression after purvalanol treatment is under control of upstream MAPK signaling axis in MCF-7 breast cancer cells
(Tubitak Scientific & Technical Research Council Turkey, Ataturk Bulvarı No 221, Kavaklıdere, Ankara, 00000, Turkey, 2014)
Roscovitine and purvalanol are specific cyclin-dependent kinase (CDK) inhibitors, which induce apoptosis by triggering cell cycle arrest in various cancer cells such as colon, prostate, and breast cancer cells. Although ...