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Q-VD-OPh, a pancaspase inhibitor, reduces trauma-induced apoptosis and improves the recovery of hind-limb function in rats after spinal cord injury 

Colak, A.; Antar, Veysel; Karaoğlan, Alper; Akdemir, Osman; Şahan, E.; Çelik, Özge; Sagmanlıgil, Ayhan (Soc Espanola Neurocirugia, C/O Dr Poza, Gran Via Salzillo 42, 30005 Murcia, Spain, 2009-12)
Background. Various caspases have been implicated in the development of secondary damage after spinal cord injury (SCI). Anticaspase therapy that targets only one caspase has been investigated in a variety of in vitro and ...
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Inhibition of PI3K signaling triggered apoptotic potential of curcumin which is hindered by Bcl-2 through activation of autophagy in MCF-7 cells 

Akkoç, Yunus; Berrak, Özge; Arısan, Elif Damla; Obakan Yerlikaya, Pınar; Çoker Gürkan, Ajda; Palavan Ünsal, Zeynep Narçın (Elsevier France-Editions Scientifiques Medicales Elsevier, 23 Rue Linois, 75724 Paris, France, 2015-04)
Curcumin is a natural anti-cancer agent derived from turmeric (Curcuma longa). Curcumin triggers intrinsic apoptotic cell death by activating mitochondrial permeabilization due to the altered expression of pro-and ...
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Calreticulin is a fine tuning molecule in epibrassinolide-induced apoptosis through activating endoplasmic reticulum stress in colon cancer cells 

Obakan Yerlikaya, Pınar; Arısan, Elif Damla; Çoker Gürkan, Ajda; Adacan, Kaan; Özbey, Utku; Somuncu, Berna; Baran, Didem; Ünsal Palavan, Zeynep Narçın (Wiley, 111 River St, Hoboken 07030-5774, NJ USA, 2017-06)
Epibrassinolide (EBR), a member of brassinostreoids plant hormones with cell proliferation promoting role in plants, is a natural polyhydroxysteroid with structural similarity to steroid hormones of vertebrates. EBR has ...
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The inhibition of PI3K and NF kappa B promoted curcumin-induced cell cycle arrest at G2/M via altering polyamine metabolism in Bcl-2 overexpressing MCF-7 breast cancer cells 

Akkoç, Yunus; Arısan, Elif Damla; Çoker Gürkan, Ajda; Obakan Yerlikaya, Pınar; Palavan Ünsal, Zeynep Narçın; Berrak, Özge (Elsevier France-Editions Scientifiques Medicales Elsevier, 23 Rue Linois, 75724 Paris, France, 2016-02)
Bcl-2 protein has been contributed with number of genes which are involved in oncogenesis. Among the many targets of Bcl-2, NF kappa B have potential role in induction of cell cycle arrest. Curcumin has potential therapeutic ...
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Epibrassinolide alters PI3K/MAPK signaling axis via activating Foxo3a-induced mitochondria-mediated apoptosis in colon cancer cells 

Coşkun, Deniz; Obakan Yerlikaya, Pınar; Arısan, Elif Damla; Çoker Gürkan, Ajda; Palavan Unsal, Narcin (Elsevier Inc, 525 B Street, Ste 1900, San Diego, Ca 92101-4495 Usa, 2015-10-15)
Epibrassinolide (EBR), a steroid-derived plant growth regulator, has been recently suggested as an apoptotic inducer in different cancer cells. In this experimental study, we investigated the potential apoptotic effect of ...
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SILAC-Based Mass Spectrometry Analysis reveals that Epibrassinolide induces apoptosis via activating Endoplasmic Reticulum stress in prostate cancer cells 

Obakan Yerlikaya, Pınar; Barrero, Carlos; Çoker Gürkan, Ajda; Arısan, Elif Damla; Merali, Salim; Ünsal Palavan, Zeynep Narçın (Public Library Science, 1160 Battery Street, Ste 100, San Francisco, Ca 94111 Usa, 2015-09-09)
Epibrassinolide (EBR) is a polyhydroxylated sterol derivative and biologically active compound of the brassinosteroids. In addition to well-described roles in plant growth, EBR induces apoptosis in the LNCaP prostate cancer ...
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Bag-1L is a Stress-withstand Molecule Prevents the Downregulation of Mcl-1 and c-Raf Under Control of Heat Shock Proteins in Cisplatin Treated HeLa Cervix Cancer Cells 

Özfiliz Kılbaş, Pelin; Arısan, Elif Damla; Çoker Gürkan, Ajda; Obakan, Pınar; Eralp, Tuğçe Nur; Dinler Doğanay, Gizem; Palavan Unsal, Narçin (Asian Pacific Organization Cancer Prevention, Apjcp Head Office, Korean Natl Cancer Center, 323 Ilan -Ro, Ilsandong-Gu, Goyang-Si, Gyeonggi-Do, 410-769, South Korea, 2014)
Background: Cisplatin, a DNA damaging agent, induces apoptosis through increasing DNA fragmentation. However, identification of intrinsic resistance molecules against Cisplatin is vital to estimate the success of therapy. ...
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FTIR spectroscopy of protein isolates of salt-tolerant soybean mutants 

Akyüz, Sevim; Akyüz, Tanıl; Çelik, Özge; Atak, Çimen (Springer, 233 Spring St, New York, Ny 10013 USA, 2018-01)
The effect of salinity on the conformation of proteins of four salt-tolerant M-2 generation mutants of soybean plants (S04-05/150-2, S04-05/150-8, S04-05/150-106, and S04-05/150-114) was investigated using Fourier transform ...
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Comparative transcriptional profiling of soybean orthologs of arabidopsis trichome developmental genes under salt stress 

Çelik, Özge; Atak, Çimen; Suludere, Zekiye (Springer, 233 Spring St, New York, Ny 10013 USA, 2018-02)
The aim of this study was to determine the ultrastructural changes and regulation of trichome-metabolism-related genes against salt stress in soybean (Glycine max L. Merr.) plants. The 14-day-old Ataem-7 and S04-05 soybean ...

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AuthorArısan, Elif Damla (6)Çoker Gürkan, Ajda (6)Obakan Yerlikaya, Pınar (5)Çelik, Özge (3)Akkoç, Yunus (2)Atak, Çimen (2)Berrak, Özge (2)Palavan Ünsal, Zeynep Narçın (2)Ünsal Palavan, Zeynep Narçın (2)Adacan, Kaan (1)... View MoreSubject
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Apoptosis (3)Death (3)Pathway (3)Activation (2)Bcl-2 (2)Curcumin (2)Growth (2)Pathways (2)PI3K (2)... View MoreDate Issued2015 (3)2018 (2)2009 (1)2014 (1)2016 (1)2017 (1)Has File(s)No (7)Yes (2)

İstanbul Kültür University

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Istanbul Kültür University, Ataköy Campus E5 Karayolu Üzeri Bakırköy 34158, İstanbul / TURKEY
Copyright © İstanbul Kültür University

Creative Commons Lisansı
IKU Institutional Repository, Creative Commons Alıntı-GayriTicari-Türetilemez 4.0 Uluslararası Lisansı ile lisanslanmıştır.

Designed by  UNIREPOS