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Bag-1L mediated chemoresistance mechanism through preventing downregulation of Mcl-1 and c-Raf by heat shock proteins in HeLa cells
(2014-11)
Background: Cisplatin, a DNA damaging agent, induces apoptosis through increasing DNA fragmentation.
However, identification of intrinsic resistance molecules against Cisplatin is vital to estimate the success of ...
Purvalanol induces endoplasmic reticulum stress mediated apoptosis and autophagy by purvalanol in HCT 116 colon cancer cells
(2015-06)
Purvalanol, a novel cyclin-dependent kinase inhibitor, is referred to as a strong apoptotic inducer which causes cell cycle arrest in various cancer cells such as prostate, breast and colon cancer cell lines. Various ...
Serotonin altered receptor tyrosine signalling pathway differently in MCF-7 and MDA-MB-231 breast cancer cells
(Spandidos Publ Ltd, Pob 18179, Athens, 116 10, Greece, 2017)
Investigation of Roscovitine (Cyc202)-Induced Apoptosis Related With Polyaminemetabolism in Mcf-7 Human Breast Cancer Cell Line
(John Wiley & Sons Inc, 111 River St, Hoboken, Nj 07030 USA, 2009-03)
EBR promotes p53 independent apoptosis in colon carcinoma cell lines
(Wiley-Blackwell, 111 River St, Hoboken 07030-5774, NJ USA, 2015-07)
Growth hormone mediated resistance against curcumin induced-apoptosis via modulating of JAK/STAT/SOCS pathway and inflammatory cytokines in MDA-MB-453 breast cancer cells
(Wiley-Blackwell, 111 River St, Hoboken 07030-5774, NJ USA, 2016-09)
The role of polyamine metabolism in curcumin induced apoptosis via reactive oxygene species (ROS) generation in growth hormone (GH) overexpressed T47D breast cancer cells
(Wiley-Blackwell, 111 River St, Hoboken 07030-5774, NJ USA, 2016-09)
Roscovitine-treated He La cells finalize autophagy later than apoptosis by downregulating Bcl-2
(Spandidos Publ Ltd, Pob 18179, Athens, 116 10, Greece, 2015-03)
The cell cycle is tightly regulated by the family of cyclin-dependent kinases (CDKs). CDKs act as regulatory factors on serine and threonine residues by phosphorylating their substrates and cyclins. CDK-targeting drugs ...
Inhibition of PI3K signaling triggered apoptotic potential of curcumin which is hindered by Bcl-2 through activation of autophagy in MCF-7 cells
(Elsevier France-Editions Scientifiques Medicales Elsevier, 23 Rue Linois, 75724 Paris, France, 2015-04)
Curcumin is a natural anti-cancer agent derived from turmeric (Curcuma longa). Curcumin triggers intrinsic apoptotic cell death by activating mitochondrial permeabilization due to the altered expression of pro-and ...
Diclofenac induced apoptosis via altering PI3K/Akt/MAPK signaling axis in HCT 116 more efficiently compared to SW480 colon cancer cells
(Springer Link, 2018-12)
Diclofenac is a preferential cyclooxygenase 2 inhibitor (COX-2) and member of non-steroidal anti-inflammatory drugs (NSAIDs). Inflammation is one of the main reason of poor prognosis of colon cancer cases; thereby NSAIDs ...