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DENSpm overcame Bcl-2 mediated resistance against Paclitaxel treatment in MCF-7 breast cancer cells via activating polyamine catabolic machinery
(Elsevier France-Editions Scientifiques Medicales Elsevier, 23 Rue Linois, 75724 Paris, France, 2016-12)Purpose: The Bcl-2 mediated resistance is one of the most critical obstacle in cancer therapy. Conventional chemotherapeutics such as Paclitaxel, a commonly used in the treatment of metastatic breast cancer, is not sufficient ... -
Diclofenac induced apoptosis via altering PI3K/Akt/MAPK signaling axis in HCT 116 more efficiently compared to SW480 colon cancer cells
(Springer Link, 2018-12)Diclofenac is a preferential cyclooxygenase 2 inhibitor (COX-2) and member of non-steroidal anti-inflammatory drugs (NSAIDs). Inflammation is one of the main reason of poor prognosis of colon cancer cases; thereby NSAIDs ... -
Distribution of peroxidase activity and polyamine pattern of Heliotropium europeum in potassium deficiency conditions
(INDERSCIENCE ENTERPRISES LTD, WORLD TRADE CENTER BLDG, 29 ROUTE DE PRE-BOIS, CASE POSTALE 896, CH-1215 GENEVA, SWITZERLAND, 2007)Polyamines, especially putrescine, are reported to increase in higher plants in response to various stressors, in particular mineral deficiency, low pH and different atmospheric pollutants. Peroxidases are another stress ... -
Downregulation of c-Myc mediated ODC expression after purvalanol treatment is under control of upstream MAPK signaling axis in MCF-7 breast cancer cells
(Tubitak Scientific & Technical Research Council Turkey, Ataturk Bulvarı No 221, Kavaklıdere, Ankara, 00000, Turkey, 2014)Roscovitine and purvalanol are specific cyclin-dependent kinase (CDK) inhibitors, which induce apoptosis by triggering cell cycle arrest in various cancer cells such as colon, prostate, and breast cancer cells. Although ... -
EBR induced autophagy in colon carcinoma cell lines
(Wiley-Blackwell, 111 River St, Hoboken 07030-5774, Nj Usa, 2015-07) -
EBR promotes p53 independent apoptosis in colon carcinoma cell lines
(Wiley-Blackwell, 111 River St, Hoboken 07030-5774, NJ USA, 2015-07) -
Effect of magnetic field and gamma radiation on Paulowinia tomentosa tissue culture
(DIAGNOSIS PRESS LTD, 67 DONDUKOV BLVD, 1504 SOFIA, BULGARIA, 2007-02)In this study Me in vitro tissue culture of the Paulownia tomentosa plant was established and a magnetic field which has 2.9-4.8mT flux density was applied to the culture at a velocity of 1m/s for 19.8 seconds. Additionally, ... -
Effect of magnetic field on peroxidase activities of soybean tissue culture
(DIAGNOSIS PRESS LTD, 67 DONDUKOV BLVD, 1504 SOFIA, BULGARIA, 2007-05)In this study, the aim was to determine the effect of magnetic field on peroxidase activities of soybean tissue culture. Shoot tips were put into petri dishes and exposed to a magnetic field for a period of 2.2 and 19.8 s ... -
Effect of polyamines on leaf rolling during drought stress in Ctenanthe setosa (Rosc.) Eichler
(2002)The effects of the three main polyamines, putrescine, spermine, and spermidine, on the degree of leaf rolling in Ctenanthe setosa were investigated. In addition, the interactions between the amounts of endogenic polyamines ... -
Effects of Air Pollution on Lung Function and Symptoms of Asthma, Rhinitis and Eczema in Primary School Children
(Springer Heidelberg, Tiergartenstrasse 17, D-69121 Heidelberg, Germany, 2013-09)Health effects of ambient air pollution were studied in three groups of schoolchildren living in areas (suburban, urban and urban-traffic) with different air pollution levels in EskiAYehir, Turkey. This study involved 1,880 ... -
Effects of Magnetic Field on Activity of Superoxide Dismutase and Catalase in Glycine max (L.) Merr. Roots
(Hard, Post-Office Box, 10-718 Olsztyn 5, Poland, 2009)Under a magnetic field the activities of superoxide dismutase (SOD) in vitro and in vivo and accompanying activities of catalase activity in vivo were investigated in soybean roots. In plant cells a magnetic field creates ... -
Effects of polyamines and polyamine biosynthetic inhibitors on mitotic activity of Allium cepa root tips
(AKADEMIAI KIADO, PRIELLE K U 19, H-1117 BUDAPEST, HUNGARY, 2008-03)The genotoxic and cytotoxic effects of exogenous polyamines (PAs), putrescine ( Put), spermidine (Spd), spermine (Spm) and PA biosynthetic inhibitors, alpha-difluoromethylornithine ( DFMO), cyclohexilamine (CHA), methylglioxal ... -
Endoplasmic reticulum stress is activated after epibrassinolide treatment leading autophagy in wild type and Atg5-/- mouse embryonic fibroblasts: a survival mechanism in nonmalignant cells
(Wiley, 111 River St, Hoboken 07030-5774, NJ USA, 2017-09) -
Enzymatic and non-enzymatic comparison of two different industrial tomato (Solanum lycopersicum) varieties against drought stress
(Springer, 233 Spring St, New York, Ny 10013 USA, 2017-08-02)Background: The aim of this study is to compare the tolerance mechanisms of two industrial tomato varieties (X5671R and 5MX12956) under drought stress. 14 days-old tomato seedlings were subjected to 7 days-long drought ... -
Epibrassinolide alters PI3K/MAPK signaling axis via activating Foxo3a-induced mitochondria-mediated apoptosis in colon cancer cells
(Elsevier Inc, 525 B Street, Ste 1900, San Diego, Ca 92101-4495 Usa, 2015-10-15)Epibrassinolide (EBR), a steroid-derived plant growth regulator, has been recently suggested as an apoptotic inducer in different cancer cells. In this experimental study, we investigated the potential apoptotic effect of ... -
Epibrassinolide-induced apoptosis regardless of p53 expression via activating polyamine catabolic machinery, a common target for androgen sensitive and insensitive prostate cancer cells
(Wiley-Blackwell, 111 River St, Hoboken 07030-5774, Nj Usa, 2014-12)BACKGROUNDEpibrassinolide (EBR), is a member of the brassinosteroids (BR), has been shown as an apoptotic inducer in different cancer cell lines. We previously showed that EBR induced apoptosis by activating polyamine ... -
Epigenetic analysis of WRKY Transcription Factor Genes in Salt Stressed Rice (Oryza sativa L.) plants
(Elsevier, 2018)It is important for plants to survive when they are subjected to environmental stress factors under different combinations in nature. In such conditions, epigenetic modifications such as cytosine methylations have a ...
