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Identification of the antioxidant defense genes which may provide enhanced salt tolerance in Oryza sativa L.
(2019-06)Antioxidative mechanisms are important to protect cells from the hazardous effects of reactive oxygen species (ROS). Salt stress is one of the environmental stress factors that leads to accumulation of ROS at toxic levels. ... -
Palbociclib, a selective CDK4/6 inhibitor, restricts cell survival and epithelial-mesenchymal transition in Panc-1 and MiaPaCa-2 pancreatic cancer cells
(2019-07)The mortality rate of pancreatic cancer has close parallels to its incidence rate because of limited therapeutics and lack of effective prognosis. Despite various novel chemotherapeutics combinations, the 5-year survival ... -
Tissue-specific transcriptional regulation of seven heavy metal stress-responsive miRNAs and their putative targets in nickel indicator castor bean (R. communis L.) plants
(ACADEMIC PRESS INC ELSEVIER SCIENCE, 525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 USA, 2019-04-15)R.communis L. has high capability to accumulate nickel which is a trace nutrient for higher plants and also an environmental contaminant causes toxicity related symptoms at higher concentrations. MicroRNAs (miRNAs) are ... -
Raman spectroscopic and chemometric investigation of lipid-protein ratio contents of soybean mutants
(1, 2019-01)Seeds belonging to fourth generation mutants (M-4) of Ataem-7 cultivar (A7) variety and S04-05 (S) breeding line salt-tolerant soybeans were investigated by Raman spectroscopy, complemented by chemometrics methods, in order ... -
Atiprimod induce apoptosis in pituitary adenoma: Endoplasmic reticulum stress and autophagy pathways
(WILEY, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, 2019-12)Pituitary adenoma is the most common tumor with a high recurrence rate due to a hormone-dependent JAK/signal transducer and activator of transcriptions (STAT) signaling. Atiprimod, a novel compound belonging to the azaspirane ... -
The molecular targets of diclofenac differs from ibuprofen to induce apoptosis and epithelial mesenchymal transition due to alternation on oxidative stress management p53 independently in PC3 prostate cancer cells
(Elsevier INC., 2019-12)Background: Prostate cancer is the most common type of cancer among men. Studies showed that the regular use of nonsteroidal antiinflammatory drugs might reduce disease progression risk for prostate cancer patients with ... -
Bag-1 Silencing Enhanced Chemotherapeutic Drug-induced Apoptosis in MCF-7 Breast Cancer Cells Affecting PI3K/Akt/mTOR and MAPK Signaling Pathways
(2019-01-19)The multifunctional anti-apoptotic Bag-1 protein has important roles in apoptosis, proteasome-mediated degradation, transcriptional regulation, and intracellular signaling. Bag-1 promotes cell survival and proliferation, ... -
Curcumin Prevented Human Autocrine Growth Hormone (GH) Signaling Mediated NF-κB Activation and miR-183-96-182 Cluster Stimulated Epithelial Mesenchymal Transition in T47D Breast Cancer Cells
(2019-02)Autocrine growth hormone (GH) signaling is a promoting factor for breast cancer via triggering abnormal cell growth, proliferation, and metastasis, drug resistance. Curcumin (diferuloylmethane), a polyphenol derived from ... -
Anti-metastatic effect of ranolazine in an in vivo rat model of prostate cancer, and expression of voltage-gated sodium channel protein in human prostate
(2019-03-20)Background Voltage-gated Na+ channels (VGSCs) are functionally upregulated in rat and human prostate cancer (PCa) where channel activity promotes cellular invasiveness in vitro and metastasis in vivo. Ranolazine is a ... -
Effect of polyamines on leaf rolling during drought stress in Ctenanthe setosa (Rosc.) Eichler
(2002)The effects of the three main polyamines, putrescine, spermine, and spermidine, on the degree of leaf rolling in Ctenanthe setosa were investigated. In addition, the interactions between the amounts of endogenic polyamines ...
