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Wnt-11 expression promotes invasiveness and correlates with survival in human pancreatic ductal adeno carcinoma
(2019-11-11)Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest forms of cancer, proving difficult to manage clinically. Wnt-11, a developmentally regulated gene producing a secreted protein, has been associated with various ... -
Aging-related diseases and autophagy
(2016)Autophagy is fundamental, evolutionary conserved physiological process at molecular level which targets long-lived cytosolic proteins and organelles to be recycled through lysosomal degradation. Diminished autophagic ... -
GMO analysis methods for food: From today to tomorrow
(2017)In the last decades, the dynamic face of biotechnology increased the number of M plants and abled the production of more precise genetically modified organisms. Since the introduction of recently developed new breeding ... -
Policy into practice on sustainable development related teaching in higher education in Turkey
(2018)This research explores the current status of implementing policy in sustainable development related teaching in higher education in Turkey. Turkish higher education policy has included increased commitment to sustainable ... -
Identification of the antioxidant defense genes which may provide enhanced salt tolerance in Oryza sativa L.
(2019-06)Antioxidative mechanisms are important to protect cells from the hazardous effects of reactive oxygen species (ROS). Salt stress is one of the environmental stress factors that leads to accumulation of ROS at toxic levels. ... -
Palbociclib, a selective CDK4/6 inhibitor, restricts cell survival and epithelial-mesenchymal transition in Panc-1 and MiaPaCa-2 pancreatic cancer cells
(2019-07)The mortality rate of pancreatic cancer has close parallels to its incidence rate because of limited therapeutics and lack of effective prognosis. Despite various novel chemotherapeutics combinations, the 5-year survival ... -
Tissue-specific transcriptional regulation of seven heavy metal stress-responsive miRNAs and their putative targets in nickel indicator castor bean (R. communis L.) plants
(ACADEMIC PRESS INC ELSEVIER SCIENCE, 525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 USA, 2019-04-15)R.communis L. has high capability to accumulate nickel which is a trace nutrient for higher plants and also an environmental contaminant causes toxicity related symptoms at higher concentrations. MicroRNAs (miRNAs) are ... -
Raman spectroscopic and chemometric investigation of lipid-protein ratio contents of soybean mutants
(1, 2019-01)Seeds belonging to fourth generation mutants (M-4) of Ataem-7 cultivar (A7) variety and S04-05 (S) breeding line salt-tolerant soybeans were investigated by Raman spectroscopy, complemented by chemometrics methods, in order ... -
Atiprimod induce apoptosis in pituitary adenoma: Endoplasmic reticulum stress and autophagy pathways
(WILEY, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, 2019-12)Pituitary adenoma is the most common tumor with a high recurrence rate due to a hormone-dependent JAK/signal transducer and activator of transcriptions (STAT) signaling. Atiprimod, a novel compound belonging to the azaspirane ...
