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Serum Adipocytokine Levels in Prostate Cancer Patients

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Author
Arısan, Elif Damla
Arısan, Serdar
Atış, Gökhan
Palavan Ünsal, Narçin
Ergenekon, Erbil
Type
Article
Date
2009
Language
en_US
Metadata
Show full item record
Abstract
Introduction: We estimated the circulating levels of adipocytokines such as adiponectin and leptin in nonobese nondiabetic prostate cancer (PCa) patients and compared the results with controls and benign prostate hyperplasia (BPH) patients. Material and Methods: Fifty patients with PCa, 20 patients with BPH and 50 healthy volunteers were entered into the study. Their blood samples were investigated for adipocytokines with the ELISA method. Results: Adiponectin levels were determined as 8.9 and 5.5 mu g/ml for the same patients. Leptin concentration was 14.78 ng/ml in organ-confined PCa patients, and 15.24 ng/ml in advanced PCa patients. In control patients, adiponectin and leptin levels were 18.4 and 12.98 ng/ml, respectively. Conclusion: Serum adipocytokine levels of PCa patients were significantly different from those of controls and BPH patients who were not obese or diabetic. Therefore, further molecular investigation of these adipocytokines will help understand the mechanism. Copyright (C) 2009 S. Karger AG, Basel
Subject
Prostate cancer
Insulin
Adiponectin
radical prostatectomy
leptin
obesity
adiponectin
risk
adipokines
insulin
weight
breast
Prostat kanseri
şişmanlık
İnsülin
radikal prostatektomi
ağırlık
URI
http://hdl.handle.net/11413/1288
Collections
  • Makaleler / Articles [140]
  • Scopus Publications [724]
  • WoS Publications [1016]

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İstanbul Kültür University

Hakkında |Politika | Kütüphane | İletişim | Send Feedback | Admin

Istanbul Kültür University, Ataköy Campus E5 Karayolu Üzeri Bakırköy 34158, İstanbul / TURKEY
Copyright © İstanbul Kültür University

Creative Commons Lisansı
IKU Institutional Repository, Creative Commons Alıntı-GayriTicari-Türetilemez 4.0 Uluslararası Lisansı ile lisanslanmıştır.

Designed by  UNIREPOS