Browsing by Subject "HYDROGEN-PEROXIDE"

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Cisplatin overcomes Bcl-2-mediated resistance to apoptosis via preferential engagement of Bak: critical role of Noxa-mediated lipid peroxidation

Kütük, Özgür; Arısan, Elif Damla; Tezil, Tuğsan; Shoshan, Maria C.; Başağa, Hüveyda (Oxford University Press, 2009-09-01)

Increased expression of antiapoptotic Bcl-2 proteins confers therapeutic resistance in various cancer types. Targeting Bcl-2 proteins by small molecules or activating alternative pathways to bypass Bcl-2-mediated protection ...