Browsing by Author "Ünsal, Zeynep Narçin"
Now showing items 1-20 of 66
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24-Epibrassinolide Induces SSAT and Causes Caspase-Dependent Apoptosis In Different Prostate Cancer Cell Lines
Obakan Yerlikaya, Pınar; Arısan, Elif Damla; Bolkent, Şehnaz; Ünsal, Zeynep Narçin (2011) -
Autocrine Growth Hormone-Triggered Curcumin Resistance Abolished by NF-κB Signaling Pathway Dependent on Inflammatory Cytokines and Active Polyamine Catabolic Machinery in MCF-7, MDA-MB-453 and MDA-MB-231 Breast Cancer Cells
Çoker Gürkan, Ajda; Çelik, Merve; Uğur, Merve; Arısan, Elif Damla; Obakan Yerlikaya, Pınar; Ünsal, Zeynep Narçin (2017)Autocrine Growth Hormone (GH) induces cell growth, proliferation metastasis in breast cancer. Curcumin is a promising therapeutic agent in cancer through affecting different molecular targets. Our aim was to demonstrate ... -
Bag-1L mediated chemoresistance mechanism through preventing downregulation of Mcl-1 and c-Raf by heat shock proteins in HeLa cells
Eralp, Tuğçe Nur; Arısan, Elif Damla; Özfiliz, Pelin; Obakan Yerlikaya, Pınar; Çoker Gürkan, Ajda; Dinler Doğanay, Gizem; Ünsal, Zeynep Narçin (2014-11)Background: Cisplatin, a DNA damaging agent, induces apoptosis through increasing DNA fragmentation. However, identification of intrinsic resistance molecules against Cisplatin is vital to estimate the success of ... -
Celastrol Modulates Lipid Synthesis via PI3K/Akt/mTOR Signaling Axis to finalize Cell Death Response in Prostate Cancer Cells
Arısan, Elif Damla; Rencüzoğulları, Özge; Çoker Gürkan, Ajda; Obakan Yerlikaya, Pınar; Ünsal, Zeynep Narçin (2017)FASN is key enzyme during lipid biogenesis is associated with prostate cancer. In this study, we aim to investigate the potential role of celastrol, root extracts of Tripterygium wilfordii on modulation of lipid ... -
Combined Treatment of Roscovitine and DFMO Induced Caspase Dependent Apoptosis in MCF-7 cells. 2nd
Obakan Yerlikaya, Pınar; Arısan, Elif Damla; Ünsal, Zeynep Narçin; Çoker Gürkan, Ajda (2010) -
Comparison of the effect of different cytokinins on chlorophyll, protein content and peroxidase activity
Ünsal, Zeynep Narçin; Çağ, Serap; Arısan, Elif Damla (2001) -
Comparison of the effects of meta-topolin and other cytokinins on chlorophyll and protein contents and peroxidase activity in cucumber cotyledons
Çağ, Serap; Arısan, Elif Damla; Ünsal, Zeynep Narçin; Arısan, Elif Damla (Taylor and Francis Online, 2003)Cytokinins play an important role in controlling many of the processes that contribute to plant senescence. The aim of this study was to compare the effect of different cytokinins, especially the new aromatic cytokinin ... -
Cox-2 inhibitor ibuprofen induced apoptosis via altering different signalling routes in HT-29 and DLD-1 colon cancer cells
Yalçın, Gizem Damla; Arısan, Elif Damla; Çoker Gürkan, Ajda; Obakan Yerlikaya, Pınar; Ünsal, Zeynep Narçin (2015) -
Curcumin induced-apoptotic cell death in GH overexpressed MDA-MB-231 breast cancer in time dependent manner
Çelik, Merve; Çoker Gürkan, Ajda; Arısan, Elif Damla; Obakan Yerlikaya, Pınar; Ünsal, Zeynep Narçin (2015) -
Curcumin Prevented Human Autocrine Growth Hormone (GH) Signaling Mediated NF-κB Activation and miR-183-96-182 Cluster Stimulated Epithelial Mesenchymal Transition in T47D Breast Cancer Cells
Obakan Yerlikaya, Pınar; Çoker Gürkan, Ajda; Bulut, Derya; Genç, Recep; Arısan, Elif Damla; Ünsal, Zeynep Narçin; Palavan-Unsal, Narcin (2019-02)Autocrine growth hormone (GH) signaling is a promoting factor for breast cancer via triggering abnormal cell growth, proliferation, and metastasis, drug resistance. Curcumin (diferuloylmethane), a polyphenol derived from ... -
Cyclin Dependent Kinase Inhibitors Modulates Polyamine Metabolism in MDA-MB-231 Cells
Ünsal, Zeynep Narçin; Arısan, Elif Damla; Obakan Yerlikaya, Pınar; Çoker Gürkan, Ajda; Özdemir, İpek (2010) -
Cytokine network is critical in growth hormone-induced resistance mechanism against curcumin which modulates JAK/STAT/SOCS pathway in MDA-MB-231 and MCF-7 breast cancer cells
Çelik, Merve; Çoker Gürkan, Ajda; Arısan, Elif Damla; Obakan Yerlikaya, Pınar; Ünsal, Zeynep Narçin (2016) -
Diclofenac induced apoptosis via altering PI3K/Akt/MAPK signaling axis in HCT 116 more efficiently compared to SW480 colon cancer cells
Arısan, Elif Damla; Ergül, Zehragül; Bozdağ, Gülnihal; Rencüzoğulları, Özge; Çoker Gürkan, Ajda; Obakan Yerlikaya, Pınar; Coşkun, Deniz; Ünsal, Zeynep Narçin (Springer Link, 2018-12)Diclofenac is a preferential cyclooxygenase 2 inhibitor (COX-2) and member of non-steroidal anti-inflammatory drugs (NSAIDs). Inflammation is one of the main reason of poor prognosis of colon cancer cases; thereby NSAIDs ... -
Diethylnorspermine (DENSpm) Induced Apoptosis in SW480 Colon Cancer Cells
İlhan, Halime; Çoker Gürkan, Ajda; Arısan, Elif Damla; Obakan Yerlikaya, Pınar; Ünsal, Zeynep Narçin (2012) -
Diminished Cyclin Dependent Kinase Activity and mTOR Are Critical In The Cell Death DecisionThrough Affecting STAT Signalling Differently In Prostate Cancer Cells
Arısan, Elif Damla; Gümüşkaptan, Çağrı; Berrak, Özge; Obakan Yerlikaya, Pınar; Çoker Gürkan, Ajda; Ünsal, Zeynep Narçin (2017) -
EBR induced autophagy in colon carcinoma cell lines
Adacan, Kaan; Obakan Yerlikaya, Pınar; Arısan, Elif Damla; Çoker Gürkan, Ajda; Ünsal, Zeynep Narçin (2015-07) -
Effect of polyamines on leaf rolling during drought stress in Ctenanthe setosa (Rosc.) Eichler
Kadıoğlu, Asim; Turgut, Rabiye; Ünsal, Zeynep Narçin; Saruhan, Neslihan (2002)The effects of the three main polyamines, putrescine, spermine, and spermidine, on the degree of leaf rolling in Ctenanthe setosa were investigated. In addition, the interactions between the amounts of endogenic polyamines ... -
Endoplasmic reticulum stress is activated after epibrassinolide treatment leading autophagy in wild type and Atg5/ mouse embryonic fibroblasts: a survival mechanism in nonmalignant cells.
Adacan, Kaan; Obakan Yerlikaya, Pınar; Arısan, Elif Damla; Çoker Gürkan, Ajda; Ünsal, Zeynep Narçin (2017)Autophagy is a process of cellular selfdegradation during which macromolecules, damaged/aged organelles and proteins are delivered to the lysosome by engulfment within doublemembrane vesicles. The accumulation of ... -
Endoplasmic reticulum stress is involved in EBR-induced autophagy in colon cancer cell lines
Obakan Yerlikaya, Pınar; Arısan, Elif Damla; Çoker Gürkan, Ajda; Ünsal, Zeynep Narçin (2014) -
Endoplasmic reticulum stress is involved in EBR-induced autophagy in colon cancer cell lines
Obakan Yerlikaya, Pınar; Arısan, Elif Damla; Çoker Gürkan, Ajda; Ünsal, Zeynep Narçin (2014)