Now showing items 1-10 of 13
SILAC-Based Mass Spectrometry Analysis reveals that Epibrassinolide induces apoptosis via activating Endoplasmic Reticulum stress in prostate cancer cells
(Public Library Science, 1160 Battery Street, Ste 100, San Francisco, Ca 94111 Usa, 2015-09-09)
Epibrassinolide (EBR) is a polyhydroxylated sterol derivative and biologically active compound of the brassinosteroids. In addition to well-described roles in plant growth, EBR induces apoptosis in the LNCaP prostate cancer ...
Epibrassinolide alters PI3K/MAPK signaling axis via activating Foxo3a-induced mitochondria-mediated apoptosis in colon cancer cells
(Elsevier Inc, 525 B Street, Ste 1900, San Diego, Ca 92101-4495 Usa, 2015-10-15)
Epibrassinolide (EBR), a steroid-derived plant growth regulator, has been recently suggested as an apoptotic inducer in different cancer cells. In this experimental study, we investigated the potential apoptotic effect of ...
Purvalanol induces endoplasmic reticulum stress mediated apoptosis and autophagy by purvalanol in HCT 116 colon cancer cells
Purvalanol, a novel cyclin-dependent kinase inhibitor, is referred to as a strong apoptotic inducer which causes cell cycle arrest in various cancer cells such as prostate, breast and colon cancer cell lines. Various ...
Roscovitine-treated He La cells finalize autophagy later than apoptosis by downregulating Bcl-2
(Spandidos Publ Ltd, Pob 18179, Athens, 116 10, Greece, 2015-03)
The cell cycle is tightly regulated by the family of cyclin-dependent kinases (CDKs). CDKs act as regulatory factors on serine and threonine residues by phosphorylating their substrates and cyclins. CDK-targeting drugs ...
Inhibition of PI3K signaling triggered apoptotic potential of curcumin which is hindered by Bcl-2 through activation of autophagy in MCF-7 cells
(Elsevier France-Editions Scientifiques Medicales Elsevier, 23 Rue Linois, 75724 Paris, France, 2015-04)
Curcumin is a natural anti-cancer agent derived from turmeric (Curcuma longa). Curcumin triggers intrinsic apoptotic cell death by activating mitochondrial permeabilization due to the altered expression of pro-and ...
Investigation the potential role of FoxO members in the purvalanol and roscovitine-induced autophagy in LNCaP and DU 145 prostate cancer cells
(Wiley-Blackwell, 111 River St, Hoboken 07030-5774, NJ USA, 2015-07-04)
Lack of functional p53 renders DENSpm-induced autophagy and apoptosis in time dependent manner in colon cancer cells
(Springer Wien, Sachsenplatz 4-6, Po Box 89, A-1201 Wien, Austria, 2015-01)
Polyamines (PAs), such as putrescine, spermidine and spermine, are alkyl-amines that are essential for cell growth, proliferation, differentiation and cancer progression in eukaryotic cells. A designed PA analogue; DENSpm, ...
EBR promotes p53 independent apoptosis in colon carcinoma cell lines
(Wiley-Blackwell, 111 River St, Hoboken 07030-5774, NJ USA, 2015-07)
EBR induced autophagy in colon carcinoma cell lines
(Wiley-Blackwell, 111 River St, Hoboken 07030-5774, Nj Usa, 2015-07)
Fetuin-A 742 (C/T) and 766 (C/G) polymorphic sites are associated with increased risk of myocardial infarction in older patients (40 years of age)
(Spandidos Publ Ltd, Pob 18179, Athens, 116 10, Greece, 2015-07)
Inflammation and genetics have key roles in the pathogenesis of atherosclerosis, and the etiology of myocardial infarction (MI). Recent studies have indicated that lower serum levels of fetuin-A may accelerate the vascular ...