Browsing by Author "Altun, Seyhan"

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Anti-metastatic effect of ranolazine in an in vivo rat model of prostate cancer, and expression of voltage-gated sodium channel protein in human prostate

Altun, Seyhan; Bugan, İlknur; Küçük, Selma; Karagöz, Zeynep; Fraser, SP; Kaya, Handan; Dodson; Foster, Cs; Djamgoz, Mba (2019-03-20)

Background Voltage-gated Na+ channels (VGSCs) are functionally upregulated in rat and human prostate cancer (PCa) where channel activity promotes cellular invasiveness in vitro and metastasis in vivo. Ranolazine is a ...